
ROME—Iran and the United States are poised to resume nuclear negotiations in Rome on Saturday, in a renewed effort to bridge a decades-long impasse over Tehran’s atomic programme.
The talks, taking place under the looming threat of potential U.S. military action, come as President Donald Trump reasserts his hardline stance. “I’m for stopping Iran, very simply, from having a nuclear weapon. They can’t have a nuclear weapon. I want Iran to be great and prosperous and terrific,” he told reporters on Friday.
Iranian Foreign Minister Abbas Araqchi and Trump’s Middle East envoy, Steve Witkoff, are expected to engage in indirect discussions mediated by Omani officials. This follows a first round in Muscat last week, which both sides described as constructive.
Despite signs of progress, Tehran has sought to temper expectations, cautioning against the assumption that sanctions relief is imminent. Iran’s Supreme Leader, Ayatollah Ali Khamenei, remarked this week that he remains “neither overly optimistic nor pessimistic” about the negotiations.
Trump, who withdrew from the 2015 nuclear accord during his first term and reinstated harsh sanctions, has ramped up pressure since returning to office in January. Washington is demanding that Iran cease its enrichment of uranium to levels it believes could lead to the development of nuclear weapons.
Tehran, for its part, insists its nuclear programme is strictly for peaceful purposes. Officials have signalled a willingness to discuss limits on enrichment in exchange for sanctions relief, but are demanding firm guarantees that the U.S. will not walk away from any future agreement, as it did in 2018.
Since 2019, Iran has significantly exceeded the uranium enrichment limits set by the 2015 deal, amassing stockpiles far beyond what Western powers deem necessary for civilian energy use. It has also ruled out negotiations over its missile programme or other aspects of its military capabilities.
Although both sides have publicly committed to diplomacy, substantial differences remain. The two countries have not engaged in direct nuclear talks since 2015. Last week’s brief interaction between Araqchi and Witkoff marked a rare moment of contact, but Saturday’s discussions in Rome will again proceed indirectly, facilitated by Omani intermediaries.